Near UV Photo-Degradation of IgG1-Fc Promoted by His and Fe(III): Probing the Role of the Metal-Binding Pocket by Site-Directed Mutagenesis

Maribel Espinoza Ballesteros, Marcela Solis Rodriguez, Steve Seibold, Kevin P. Battaile, Scott Lovell, Thomas J. Tolbert, Christian Schöneich

Molecular Pharmaceutics

Crystal structure of Plasmodium vivax macrophage migration inhibitory factor

Aryana Nair, Matthew Lin, Arav Srivastava, Lijun Liu, Anne Cooper, Kevin Battaile, Elizabeth Harmon, Peter J. Myler, Bart L. Staker, Scott Lovell, Graham Chakafana, Oluwatoyin A. Asojo

Acta Crystallographica Section F Structural Biology Communications, Vol. 82, Issue 6, Pages 194-200

Structure-Guided Design of Calcium-Dependent Protein Kinase 1 Inhibitors for Cryptosporidiosis

Wissarut Wijitrmektong, Ryan Choi, Matthew A Hulverson, Lijun Liu, Anne Cooper, Kevin P Battaile, Elizabeth K Harmon, Denise Ann Dayao, Lauren Huerta, Saul Tzipori, Case W McNamara, Malina A Bakowski, Scott Lovell, Wesley C Van Voorhis, Gregory D Cuny

The Journal of Infectious Diseases

Structural analyses of Trichomonas vaginalis pyrophosphate-dependent phosphofructokinase (TvPPi-PFK)

Avery Chiu, Lijun Liu, Steve Seibold, Kevin Battaile, Justin Craig, Elizabeth Harmon, Sandhya Subramanian, Lisabeth Cron, Bart Staker, Peter J Myler, Scott Lovell, Wesley C. Van Voorhis, Graham Chakafana, Oluwatoyin A. Asojo

A Trichomonas vaginalis C2-XYPPX-repeat protein with a structured C2 domain displaying dampened flexibility upon binding calcium

Garry W. Buchko, Lijun Liu, Kevin P. Battaile, Justin K. Craig, Elizabeth K. Harmon, Wesley C. Van Voorhis, Peter J. Myler, Scott Lovell

Biochimie, Vol. 241, Pages 44-55

Structure, Function, and Inhibition of Adenylosuccinate Lyase (ADSL) from Mycobacterium tuberculosis

Vigyasa Singh, Devi Jaganathan, Jamie Corro, Ke Chen, Subodh Kumar Samrat, Ran Zhang, Mengjiao Ma, Kevin P. Battaile, Zhong Li, Qing-Yu Zhang, Rui Xiong, Anil K. Ojha, Hongmin Li

ACS Infectious Diseases, Vol. 12, Issue 1, Pages 74-90

Structural Analysis and Inhibitor Modeling of Bacterioferritin From Brucella abortus.

Lijun Liu, Elizabeth K. Harmon, Justin K. Craig, Huili Yao, Kevin P. Battaile, David K. Johnson, Sandhya Subramanian, Wesley C. Van Voorhis, Mario Rivera, Scott Lovell

Proteins, Vol. 94, Issue 6, Pages 1170-1181

Discovery and mechanism of a highly selective, antifungal acetyl-CoA synthetase inhibitor

Andrew J. Jezewski, Katy M. Alden, Jonah Propp, Drashti G. Daraji, Charles L. Lail, Michael E. Heene, Andrew J. Fuller, Jeffery C. Ferreira, Lijun Liu, Kevin P. Battaile, Noelle S. Williams, Bart L. Staker, Scott Lovell, Timothy J. Hagen, Damian J. Krysan

Nature Communications, Vol. 16, Issue 1

Inhibitors of the Bacterioferritin Ferredoxin Complex Dysregulate Iron Homeostasis and Kill Acinetobacter baumannii and Biofilm-Embedded Pseudomonas aeruginosa Cells

Alexanndra M. Behm, Huili Yao, Emmanuel C. Eze, Suliat A. Alli, Simon D. P. Baugh, Ebenezer Ametsetor, Kendall M. Powell, Kevin P. Battaile, Steve Seibold, Scott Lovell, Richard A. Bunce, Allen B. Reitz, Mario Rivera

ACS Infectious Diseases, Vol. 11, Issue 7, Pages 1983-1993

Crystal structure of N-terminally hexahistidine-tagged Onchocerca volvulus macrophage migration inhibitory factor-1

Amber D. Kimble, Omolara C. O. Dawson, Lijun Liu, Sandhya Subramanian, Anne Cooper, Kevin Battaile, Justin Craig, Elizabeth Harmon, Peter Myler, Scott Lovell, Oluwatoyin A. Asojo

Acta Crystallographica Section F Structural Biology Communications, Vol. 80, Issue 12, Pages 328-334

Structures of Trichomonas vaginalis macrophage migratory inhibitory factor

Aruesha Srivastava, Aryana Nair, Omolara C. O. Dawson, Raymond Gao, Lijun Liu, Justin K. Craig, Kevin P. Battaile, Elizabeth K. Harmon, Lynn K. Barrett, Wesley C. Van Voorhis, Sandhya Subramanian, Peter J. Myler, Scott Lovell, Oluwatoyin A. Asojo, Rabih Darwiche

Acta Crystallographica Section F Structural Biology Communications, Vol. 80, Issue 12, Pages 341-347

A single Leishmania adenylate–forming enzyme of the ANL superfamily generates both acetyl- and acetoacetyl-CoA

Andrew J. Jezewski, Taiwo E. Esan, Jonah Propp, Andrew J. Fuller, Drashti G. Daraji, Charles Lail, Bart L. Staker, Elijah L. Woodward, Linjun Liu, Kevin P. Battaile, Scott Lovell, Timothy J. Hagen, Damian J. Krysan

Journal of Biological Chemistry, Vol. 300, Issue 11, Pages 107879

Mechanistic Studies of Small Molecule Ligands Selective to RNA Single G Bulges

Shalakha Hegde, Sana Akhter, Zhichao Tang, Chang Qi, Chenguang Yu, Anna Lewicka, Yu Liu, Kushal Koirala, Mikhail Reibarkh, Kevin P. Battaile, Anne Cooper, Scott Lovell, Erik D. Holmstrom, Xiao Wang, Joseph A. Piccirilli, Qi Gao, Yinglong Miao, Jingxin Wang

Structure-Guided Design of Potent Coronavirus Inhibitors with a 2-Pyrrolidone Scaffold: Biochemical, Crystallographic, and Virological Studies

Chamandi S. Dampalla, Yunjeong Kim, Alexandria Zabiegala, Dennis J. Howard, Harry Nhat Nguyen, Trent K. Madden, Hayden A. Thurman, Anne Cooper, Lijun Liu, Kevin P. Battaile, Scott Lovell, Kyeong-Ok Chang, William C. Groutas

Journal of Medicinal Chemistry, Vol. 67, Issue 14, Pages 11937-11956

HSV-1 ICP0 Dimer Domain Adopts a Novel β-barrel Fold

Erick McCloskey, Maithri Kashipathy, Anne Cooper, Philip Gao, David K. Johnson, Kevin P. Battaile, Scott Lovell, David J. Davido

<i>Pseudomonas aeruginosa</i> Dps (PA0962) Functions in H₂O₂ Mediated Oxidative Stress Defense and Exhibits In Vitro DNA Cleaving Activity

Nimesha Rajapaksha, Anabel Soldano, Huili Yao, Fabrizio Donnarumma, Maithri M. Kashipathy, Steve Seibold, Kevin P. Battaile, Scott Lovell, Mario Rivera

International Journal of Molecular Sciences, Vol. 24, Issue 5, Pages 4669

Improving the kinetic parameters of nicotine oxidizing enzymes by homologous structure comparison and rational design

Dwight O. Deay, Steve Seibold, Kevin P. Battaile, Scott Lovell, Mark L. Richter, Peter A. Petillo

Archives of Biochemistry and Biophysics, Vol. 718, Pages 109122

Structure-Guided Design of Potent Inhibitors of SARS-CoV-2 3CL Protease: Structural, Biochemical, and Cell-Based Studies

Chamandi S. Dampalla, Athri D. Rathnayake, Krishani Dinali Perera, Abdul-Rahman M. Jesri, Harry Nhat Nguyen, Matthew J. Miller, Hayden A. Thurman, Jian Zheng, Maithri M. Kashipathy, Kevin P. Battaile, Scott Lovell, Stanley Perlman, Yunjeong Kim, William C. Groutas, Kyeong-Ok Chang

Journal of Medicinal Chemistry, Vol. 64, Issue 24, Pages 17846-17865