Biography

As a postdoc, I am studying structural heterogeneity in RNA ensembles using single particle Cryo-EM. I am associated also with Rockefeller University and the Flatiron Institute

Publications

Pre-mRNA Splicing Factor U2AF2 Recognizes Distinct Conformations of Nucleotide Variants at the Center of the pre-mRNA Splice Site Signal

Eliezra Glasser, Debanjana Maji, Giulia Biancon, Anees Mohammed Keedakkatt Puthenpeedikakkal, Chapin E. Cavender, Toma Tebaldi, Mary J. Pulvino, Jermaine L. Jenkins, David H. Mathews, Stephanie Halene, Clara L. Kielkopf

2021 September

Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing

Debanjana Maji, Eliezra Glasser, Steven Henderson, Justin Galardi, Mary J. Pulvino, Jermaine L. Jenkins, Clara L. Kielkopf

Journal of Biological Chemistry, Vol. 295, Issue 50, Pages 17148-17157

2020 December

Structures of SF3b1 reveal a dynamic Achilles heel of spliceosome assembly: Implications for cancer-associated abnormalities and drug discovery

Debanjana Maji, Alan Grossfield, Clara L. Kielkopf

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, Vol. 1862, Issue 11-12, Pages 194440

2019 November

The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface

Sarah Loerch, Justin R. Leach, Steven W. Horner, Debanjana Maji, Jermaine L. Jenkins, Mary J. Pulvino, Clara L. Kielkopf

Journal of Biological Chemistry, Vol. 294, Issue 8, Pages 2892-5793

2019 February