X-Ray Publications


Green CM, Li Z, Smith AD, Novikova O, Bacot-Davis VR, Gao F, Hu S, BanavaliNK, Thiele DJ, Li H, Belfort M. Spliceosomal Prp8 intein at the crossroads ofprotein and RNA splicing. PLoS Biol. 2019 Oct 10;17(10):e3000104. doi:10.1371/journal.pbio.3000104. eCollection 2019 Oct. PubMed PMID: 31600193; PubMedCentral PMCID: PMC6805012.


Noreen Z, Jobichen C, Abbasi R, Seetharaman J, Sivaraman J, Bokhari H. Structural basis for the pathogenesis of Campylobacter jejuni Hcp1, a structural and effector protein of the Type VI Secretion System. FEBS J. 2018 Nov;285(21):4060-4070. doi: 10.1111/febs.14650. Epub 2018 Sep 21. PubMed PMID: 30194714.


Orlova N, Gerding M, Ivashkiv O, Olinares PDB, Chait BT, Waldor MK, Jeruzalmi D, The replication initiator of the cholera pathogen’s second chromosome shows structural similarity to plasmid initiators.  Nucleic Acids Res, 2017 Apr 20;45(7):3724-3737.  PMCID: PMC28031373.  Link


Lewis-Ballester A, Forouhar F, Kim SM, Lew S, Wang Y, Karkashon S, Seetharaman J, Batabyal D, Chiang BY, Hussain M, Correia MA, Yeh SR, Tong L.  Molecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2,3-dioxygenase Sci Rep. 2016 Oct 20;6:35169. doi: 10.1038/srep35169. PMCID:  PMC5071832. Link


Clarke OB, Tomasek D, Jorge CD, Dufrisne MB, Kim M, Banerjee S, Rajashankar KR, Shapiro L, Hendrickson WA, Santos H, Mancia F. Structural basis for phosphatidylinositol-phosphate biosynthesis. Nat Commun. 2015 Oct 16;6:8505. PubMed Central PMCID: PMC4634129. Link

Q. Liu and W.A. Hendrickson. Crystallographic Phasing from Weak Anomalous Signals. Curr. Opin. Struct. Biol. 34, 99-107 (2015). PubMed Central PMCID: PMC4684729. Link

F.M. Ranaivoson, Q. Liu, F. Martini, F. Bergami, S. von Daake, S. Li, D. Lee, B. Demeler, W.A. Hendrickson and D. Comoletti, Structural and mechanistic insights into the Latrophilin3 – FLRT3 complex that mediates glutamatergic synapse development. Structure, Sep 1; 23 (9): 1665-77 (2015). PubMed Central PMCID: PMC4930246. Link

J. Cheung, C. Ginter, M. Cassidy, M.C. Franklin, M.J. Rudolph, N. Robine, R.B. Darnell and W.A. Hendrickson, Structural Insights into Mis-regulation of Protein Kinase A in Human Tumors. Proc. Natl. Acad. Sci. USA 112, 1374-1379 (2015). PubMed Central PMCID: PMC4321305. Link

S Reeve, P Gainza, K Frey, I Georgiev, B Donald, A Anderson, Protein Design Algorithms Predict Viable Resistance to an Experimental Antifolate, Proc Natl Acad Sci USA, 112(3), 749-754 (2015). PubMed Central PMCID: PMC4311853. Link

A Fedorov, R Marti-Arbona, V Newmmara, D Hitchock, E Fedorov, S Almo, F Raushel, Structure of N-Formimino-l-glutamate Iminohydrolase from Pseudomonas Aeruginosa, Biochemistry, 54(3), 890-897 (2015). PubMed Central PMCID: PMC4357388. Link

G Bunkoczi, A McCoy, N Echols, R Grosse-Kunstleve, P Adams, J Holton, R Read, T Terwilliger, Macromolecular X-ray Structure Determination Using Weak, Single-wavelength Anomalous Data, Nat. Methods, 12, 127-130 (2015). PubMed Central PMCID: PMC4312553. Link

Y Gupta, S Chan, S Xu, A Aggarwal, Structural Basis of Asymmetric DNA Methylation and ATP-triggered Long-range Diffusion by EcoP15I, Nat. Commun., 6, 7363 (2015). PubMed Central PMCID: PMC4490356. Link


Q. Liu, Y. Guo, Y. Chang, Z. Cai, Z. Assur, F. Mancia, M.I. Greene and W.A. Hendrickson, Multi- crystal Native-SAD Analysis at 6 keV. Acta Crystallogr. D. 70, 2544-2557 (2014).

Z. Zhang, Q. Liu and W.A. Hendrickson, Crystal Structures of Apparent Saccharide Sensors from Histidine Kinase Receptors Prevalent in a Human Gut Symbiont. FEBS J. 281, 4263-4279 (2014).

W.A. Hendrickson, Anomalous Diffraction in Crystallographic Phase Evaluation. Quarterly Reviews of Biophysics 47, 49-93 (2014).

J.R. Courter, N. Madani, J. Sodroski, A. Schön, E. Freire, P.D. Kwong, W.A. Hendrickson, I.M. Chaiken, J.M. LaLonde, and A.B. Smith, III, Structure-Based Design, Synthesis and Validation of CD4-Mimetic Small Molecule Inhibitors of HIV-1 Entry: Conversion of a Viral Entry Agonist to an Antagonist. Accounts of Chemical Research 47, 1228-1237 (2014).

S Elshahawi, T Ramelot, J Seetharaman, J Chen, S Singh, Y Yang, K Pederson, M Kharel, R Xiao, et al., Structure-Guided Functional Characterization of Enediyne Self-Sacrifice Resistance Proteins, CalU16 and CalU19, ACS Chem. Biol., 9(10), 2347-2358 (2014).

R Ferrao, H Zhou, Y Shan, Q Liu, Q Li, D Shaw, X Li, H Wu, IRAK4 Dimerization and Trans-Autophosphorylation Are Induced by Myddosome Assembly, Mol. Cell, 55(6), 891-903 (2014).

D Odokonyero, A Sakai, Y Patskovsky, V Malashkevich, A Fedorov, J Bonanno, E Fedorov, R Toro, R Agarwal, et al., Loss of Quaternary Structure is Associated with Rapid Sequence Divergence in the OSBS Family, Proc Natl Acad Sci USA, 111(23), 8535-8540 (2014).

S Burmakina, Y Geng, Y Chen, Q Fan, Heterodimeric Coiled-Coil Interactions of Human GABAB Receptor, Proc Natl Acad Sci USA, 111(19), 6958-6963 (2014).

F Hsu, X Luo, J Qiu, Y Teng, J Jin, M Smolka, Z Luo, Y Mao, The Legionella Effector SidC Defines a Unique Family of Ubiquitin Ligases Important for Bacterial Phagosomal Remodeling, Proc Natl Acad Sci USA, 111(29), 10538-10543 (2014).

S Bjelic, Y Kipnis, L Wang, Z Pianowski, S Vorobiev, M Su, J Seetharaman, R Xiao, G Kornhaber, et al., Exploration of Alternate Catalytic Mechanisms and Optimization Strategies for Retroaldolase Design, J. Mol. Biol., 426(1), 256-271 (2014).

J Carrasco-Miranda, A Lopez-Zavala, A Arvizu-Flores, K Garcia-Orozco, V Stojanoff, E Rudino-Pinera, L Brieba, R Sotelo-Mundo, Crystal Structure of the Shrimp Proliferating Cell Nuclear Antigen: Structural Complementarity with WSSV DNA Polymerase PIP-Box , PLoS One, 9(4), e94369 (2014).

K Lamb, M Lombardo, J Alverson, N Priestley, D Wright, A Anderson, Crystal Structures of Klebsiella Pneumoniae Dihydrofolate Reductase Bound to Propargyl-linked Antifolates Reveal Features for Potency and Selectivity, Antimicrob. Agents Chemother., 58(12), 7484-7491 (2014).

P Harvilla, H Wolcott, J Magyar, The Structure of Ferricytochrome c552 from the Psychrophilic Marine Bacterium Colwellia Psychrerythraea 34H, Metallomics, 6, 1126-1130 (2014).