Membrane Proteins (COMPPÅ) Publications 2017-09-11T14:32:23+00:00

2017

Hirschi M, Johnson ZL, Lee S-Y. Visualizing multistep elevator-like transitions of a nucleoside transporter. Nature, in press. PMID: 28424521. Link

Su M, Gao F, Yuan Q, Mao Y, Li D, Guo Y, Yang C, Wang X, Bruni R, Kloss B, Zhao H, Zeng Y, Zhang F, Marks AR, Hendrickson WA and Chen Y. Structural Basis for Conductance through TRIC Cation Channels. Nat. Commun. 8, 15103 (2017). Open Access Publication. Link

Scaglione A, Celeste Montemiglio L, Parisi G, Asteriti IA, Bruni R, Cerutti G, Testi C, Savino C, Mancia F, Lavia P and Vallone B. Subcellular localization of the five members of the human steroid 5α−reductase family. Biochimie Open. In press.

2016

Kalathur RC, Panganiban M, Bruni R. High-Throughput Baculovirus Expression System for Membrane Protein Production. Methods Mol Biol. 2016;1432:187-202. PMID: 27485337. Link

Petrou, V. I., Herrera, C. M., Schultz, K. M., Clarke, O. B., Vendome, J., Tomasek, D., Banerjee,S., Rajashankar, K. R., Kloss, B., Kloppmann, E., Rost, B., Klug, C. S., Trent, M. S., Shapiro, L., and Mancia, F. Structures of aminoarabinose transferase ArnT suggest a molecular basis for modification of lipid A. Science. 2016 Feb 5;351(6273):608-12.PMID: 26912703. Link

Ardiccioni C, Clarke OB, Tomasek D, Issa HA, von Alpen DC, Pond HL, Banerjee S, Rajashankar KR, Liu Q, Guan Z, Li C, Kloss B, Bruni R, Kloppmann E, Rost B, Manzini MC, Shapiro L, Mancia F. Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis. Nat Commun. 2016 Jan 5;7:10175. PMID: 26729507. Link

2015

Y. Guo, R.C. Kalathur, Q. Liu, B. Kloss, R. Bruni, C. Ginter, E. Kloppmann, B. Rost and W.A. Hendrickson, Structure and Activity of Tryptophan-rich TSPO Proteins. Science 347, 551-555 (2015). PMID: PMC4341906. Link

Beltrán, J., Kloss, B., Hosler, J.P., Geng, J., Liu, A., Modi, A., Dawson, J.H., Sono, M., Shumskaya, M., Ampomah-Dwamena, C., Love, J.D., and Wurtzel, E.T. Control of carotenoid biosynthesis through a heme-based cis-trans isomerase. Nat. Chem. Biol. 11, 598-605 (2015). PMID: PMC4509827. Link

Zalk, R., O.B. Clarke, A. Georges, R.A. Grassucci, S. Reiken, F. Mancia, W.A. Hendrickson, J Frank and A.R. Marks. Structure of a mammalian ryanodine receptor. Nature 517, 44-49 (2015). PMID: PMC4300236. Link

Bai, Y., McCoy JG, Levin EJ, Sobrado P, Rajashankar KR, Fox, B.G. and Zhou, M. X-ray structure of a mammalian stearoyl-CoA desaturase. Nature 524, 252-256 (2015). PMID: PMC4689147. Link

2014

T. Yang, Q. Liu, B. Kloss, R. Bruni, R. Kalathur, Y. Guo, E. Kloppmann, B. Rost, H.M. Colecraft and W.A. Hendrickson, Structure and Selectivity in Bestrophin Ion Channels. Science 346, 355-359 (2014). PMID: PMC4341822. Link

Y. Chang, R. Bruni, B. Kloss, Z. Assur, E. Kloppmann, B. Rost, W.A. Hendrickson and Q. Liu, Structural Basis for a pH Sensitive Calcium Leak across Membranes. Science 344, 1131-1135 (2014). PMID: PMC4119810. Link

Goldberg, T., Hecht M, Hamp T, Karl T, Yachdav G, Ahmed N, Altermann U, Angerer P, Ansorge S, Balasz K, Bernhofer M, Betz A, Cizmadija L, Do KT, Gerke J, Greil R, Joerdens V, Hastreiter M, Hembach K, Herzog M, Kalemanov M, Kluge M, Meier A, Nasir H, Neumaier U, Prade V, Reeb J, Sorokoumov A, Troshani I, Vorberg S, Waldraff S, Zierer J, Nielsen, H., and Rost, B. LocTree3 prediction of localization. Nucleic Acids Res. 42, W350-355 (2014). PMID: PMC4086075. Link

Yachdav, G., Kloppmann E, Kajan L, Hecht M, Goldberg T, Hamp T, Hönigschmid P, Schafferhans A, Roos M, Bernhofer M, Richter L, Ashkenazy H, Punta M, Schlessinger A, Bromberg Y, Schneider R, Vriend G, Sander C, Ben-Tal, N., and Rost, B. PredictProtein– an open resource for online prediction of protein structural and functional features. Nucleic Acids Res. 42, W337-343 (2014). PMID: PMC4086098. Link

Huang, H., Levin EJ, Liu S, Bai Y, Lockless, S.W. and Zhou M. Structure of a membrane- embedded prenyltransferase homologous to UBIAD1. PLoS Biol. 12, e1001911 (2014). PMID: PMC4106721. Link

Sciara, G., Clarke, O.B., Tomasek, D., Kloss, B., Tabuso, S., Byfield, R., Cohn, R., Banerjee, S., Rajashankar, K.R., Slavkovic, V., Graziano, J.H., Shapiro, L., and Mancia, F. Structural basis for catalysis in a CDP-alcohol phosphotransferase. Nat. Commun. 5, 4068 (2014). PMID: PMC4098843. Link