Membrane Proteins (COMPPÅ) Publications
2018
Assur Sanghai, Z., Liu, Q., Clarke, O.B., Leal Pinto, E., Kloss, B., Tabuso, S., Love, J., Punta, M., Banerjee, S., Rajashankar. K.R., Rost, B., Logothetis, D., Quick, M., Hendrickson, W.A., and Mancia, F. Structure-based analysis of CysZ-mediated cellular uptake of sulfate. Elife 2018 May 24;7. pii: e27829. doi: 10.7554/eLife.27829. Link
Blackburn, M.R., Hubbard, C., Kiessling, V., Bi, Y., Kloss, B., Tamm, L., and Zimmer, J. Distinct reaction mechanisms for hyaluronan biosynthesis in different kingdoms of life. Glycobiology 2018 Feb 1;28(2):108-121. doi: 10.1093. Link
Saladi SM, Javed N, Müller A, and Clemons WM. A statistical model for improved membrane protein expression using sequence-derived features. J Biol Chem. 2018 Jan 29. pii: jbc.RA117.001052. doi: 10.1074/jbc.RA117.001052. Link
2017
Hirschi M, Johnson ZL, Lee S-Y. Visualizing multistep elevator-like transitions of a nucleoside transporter. Nature, in press. PMID: 28424521. Link
Su M, Gao F, Yuan Q, Mao Y, Li D, Guo Y, Yang C, Wang X, Bruni R, Kloss B, Zhao H, Zeng Y, Zhang F, Marks AR, Hendrickson WA and Chen Y. Structural Basis for Conductance through TRIC Cation Channels. Nat. Commun. 8, 15103 (2017). Open Access Publication. Link
Scaglione A, Celeste Montemiglio L, Parisi G, Asteriti IA, Bruni R, Cerutti G, Testi C, Savino C, Mancia F, Lavia P and Vallone B. Subcellular localization of the five members of the human steroid 5α−reductase family. Biochimie Open. In press.
2016
Kalathur RC, Panganiban M, Bruni R. High-Throughput Baculovirus Expression System for Membrane Protein Production. Methods Mol Biol. 2016;1432:187-202. PMID: 27485337. Link
Petrou, V. I., Herrera, C. M., Schultz, K. M., Clarke, O. B., Vendome, J., Tomasek, D., Banerjee,S., Rajashankar, K. R., Kloss, B., Kloppmann, E., Rost, B., Klug, C. S., Trent, M. S., Shapiro, L., and Mancia, F. Structures of aminoarabinose transferase ArnT suggest a molecular basis for modification of lipid A. Science. 2016 Feb 5;351(6273):608-12.PMID: 26912703. Link
Ardiccioni C, Clarke OB, Tomasek D, Issa HA, von Alpen DC, Pond HL, Banerjee S, Rajashankar KR, Liu Q, Guan Z, Li C, Kloss B, Bruni R, Kloppmann E, Rost B, Manzini MC, Shapiro L, Mancia F. Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis. Nat Commun. 2016 Jan 5;7:10175. PMID: 26729507. Link
2015
Y. Guo, R.C. Kalathur, Q. Liu, B. Kloss, R. Bruni, C. Ginter, E. Kloppmann, B. Rost and W.A. Hendrickson, Structure and Activity of Tryptophan-rich TSPO Proteins. Science 347, 551-555 (2015). PMID: PMC4341906. Link
Beltrán, J., Kloss, B., Hosler, J.P., Geng, J., Liu, A., Modi, A., Dawson, J.H., Sono, M., Shumskaya, M., Ampomah-Dwamena, C., Love, J.D., and Wurtzel, E.T. Control of carotenoid biosynthesis through a heme-based cis-trans isomerase. Nat. Chem. Biol. 11, 598-605 (2015). PMID: PMC4509827. Link
Zalk, R., O.B. Clarke, A. Georges, R.A. Grassucci, S. Reiken, F. Mancia, W.A. Hendrickson, J Frank and A.R. Marks. Structure of a mammalian ryanodine receptor. Nature 517, 44-49 (2015). PMID: PMC4300236. Link
Bai, Y., McCoy JG, Levin EJ, Sobrado P, Rajashankar KR, Fox, B.G. and Zhou, M. X-ray structure of a mammalian stearoyl-CoA desaturase. Nature 524, 252-256 (2015). PMID: PMC4689147. Link
2014
T. Yang, Q. Liu, B. Kloss, R. Bruni, R. Kalathur, Y. Guo, E. Kloppmann, B. Rost, H.M. Colecraft and W.A. Hendrickson, Structure and Selectivity in Bestrophin Ion Channels. Science 346, 355-359 (2014). PMID: PMC4341822. Link
Y. Chang, R. Bruni, B. Kloss, Z. Assur, E. Kloppmann, B. Rost, W.A. Hendrickson and Q. Liu, Structural Basis for a pH Sensitive Calcium Leak across Membranes. Science 344, 1131-1135 (2014). PMID: PMC4119810. Link
Goldberg, T., Hecht M, Hamp T, Karl T, Yachdav G, Ahmed N, Altermann U, Angerer P, Ansorge S, Balasz K, Bernhofer M, Betz A, Cizmadija L, Do KT, Gerke J, Greil R, Joerdens V, Hastreiter M, Hembach K, Herzog M, Kalemanov M, Kluge M, Meier A, Nasir H, Neumaier U, Prade V, Reeb J, Sorokoumov A, Troshani I, Vorberg S, Waldraff S, Zierer J, Nielsen, H., and Rost, B. LocTree3 prediction of localization. Nucleic Acids Res. 42, W350-355 (2014). PMID: PMC4086075. Link
Yachdav, G., Kloppmann E, Kajan L, Hecht M, Goldberg T, Hamp T, Hönigschmid P, Schafferhans A, Roos M, Bernhofer M, Richter L, Ashkenazy H, Punta M, Schlessinger A, Bromberg Y, Schneider R, Vriend G, Sander C, Ben-Tal, N., and Rost, B. PredictProtein– an open resource for online prediction of protein structural and functional features. Nucleic Acids Res. 42, W337-343 (2014). PMID: PMC4086098. Link
Huang, H., Levin EJ, Liu S, Bai Y, Lockless, S.W. and Zhou M. Structure of a membrane- embedded prenyltransferase homologous to UBIAD1. PLoS Biol. 12, e1001911 (2014). PMID: PMC4106721. Link
Sciara, G., Clarke, O.B., Tomasek, D., Kloss, B., Tabuso, S., Byfield, R., Cohn, R., Banerjee, S., Rajashankar, K.R., Slavkovic, V., Graziano, J.H., Shapiro, L., and Mancia, F. Structural basis for catalysis in a CDP-alcohol phosphotransferase. Nat. Commun. 5, 4068 (2014). PMID: PMC4098843. Link