The New York Structural Biology Center, NYSBC, is an organization of nine eminent academic research institutions. Founded in 1999, NYSBC is a not-for-profit consortium that provides advanced resources in structural biology to its members and outside users. The Center manages two facilities, its main facility in Manhattan and a crystallography facility at the National Synchrotron Light Source II (NSLS-­II) at Brookhaven National Laboratories (BNL) on Long Island. NYSBC is a global leader in structural biology with unsurpassed instrumentation and expertise whose services include high throughput gene-to-­structure determination, X-­ray crystallography, NMR spectroscopy, Cryo-­electron microscopy and Protein Production.