Examples of structures solved by NRAMM in the past few years.

For more information visit the NRAMM website: nramm.nysbc.org


The National Resource for Automated Molecular Microscopy (NRAMM) is a Biomedical Technology Research Center based at NYSBC. Our mission is to develop, test and apply technology aimed towards completely automating the processes involved in solving macromolecular structure using cryo-electron microscopy (cryoEM). Our goal is to both serve as a center for high-throughput molecular imaging and to transfer this technology to the research community.


Users applying to the Resource are asked to proceeed as follows:

  • Registration: Register an account.
  • Project Submission: Submit a Project. (If you already have an account with us)
  • Review and Selection: Your application will be reviewed by the resource executive committee (REC) with one month. Selection of projects is based primarily on scientific value and synergy with the core research and development projects. Additional consideration will be given to geographical location and inclusion of underrepresented communities.
  • Project Operation: Once the project has been accepted it will be tracked on a weekly basis. An initial interaction between the new users and the Resource staff will take place and a plan will be developed for the project.
  • Scheduling of Facility Resources: The REC will oversee the allocation of instrumentation and staff resources.


NRAMM welcomes applications of both collaborative and service projects. No direct finanacial support for collaborative and service actives is available from NRAMM.

National Resource for Automated Molecular Microscopy is supported by a grant from the National Institute of General Medical Sciences (9 P41 GM103310) from the National Institutes of Health.