New York Structural Biology Center

Temporary update

FACILITIES (EM, X-ray, NMR, IT)

Mission | Participants | Location | Laboratories | Seminars & Courses
| Jobs | Implementation |Contact |Publications, preprints and reprints |Other related material

NEWS

Mission

The New York Structural Biology Center (NYSBC) is a state-of-the-art research center being developed cooperatively by ten outstanding research centers. The Center houses the largest and most advanced cluster of high-field research magnets (NMRs) in the United States in its first phase. An additional phase includes a state-of-the-art cryo Electron Microscopes and sample preparation resources, and will expand with additional microscopes. NYSBC is the organizer for the Participating Research Team at beam lines X4A and X4C at Brookhaven National Laboratory.

Research conducted at the Center will significantly increase our understanding of the role that proteins play in disease pathways and enhance the ability of scientists to carry out advanced biomedical research in a number of areas including the new fields of structural genomics, and proteomics. The NYSBC is bringing together a nexus of scientific talent to generate the sort of collaborative creative community that spawns new technologies and sparks new discoveries.

Participants

The New York Structural Biology Center is a 501 (c) (3) corporation incorporated in the State of New York. The corporation is governed by a Board representing ten institutional members. The institutional members are: Albert Einstein College of Medicine of Yeshiva University , City University of New York , Columbia University , Memorial Sloan-Kettering Cancer Center , Mount Sinai School of Medicine , New York University , The Rockefeller University , Wadsworth Center of the Department of Health , the Joan and Sanford Weill Medical College of Cornell University , and the State University of New York .

Faculty, postdocs, and students of the Member Institutions can become affiliates of the Center, and details are at the Center’s intranet. The Center supports the work of more than 60 laboratories within these institutions.

The momentum created by the New York Structural Biology Center has been fueled by an exceptional core group of scientists from the participating institutions who have taken an active role in the Center's development since its inception. The group has been expanded to include other scientists from throughout the area to develop plans for collaborative research projects and future expansion of the facility.

Location

The New York Structural Biology Center is located in its own building leased from CUNY adjacent to the City College campus of the City University of New York at Convent Avenue and 133rd Street. There's a link for more details about getting to the Center.

The facility includes a 22,000 square foot newly renovated building housing the high-field magnets and a phase II area of more than 12,000 square foot addition built to accommodate additional magnets, laboratories, computers, other new initiatives, and office and classroom space. This has been built with funds from NIH and the City of New York. A third building, predominantly for cryo electron microscopy, is in the final stages of construction, supported by funds from NYSTAR and NIH.

Implementation

The New York Structural Biology Center's facilities are operational. At 4q 2005, for cryo electron microscopy, there is a 200 kV FEG microscope and a 120 kV microscope, with ancillary equipment. For the beam line operations, see the X4a beamline page. For NMR, one 900 MHz system, three 800 MHz spectrometers, a 750/89, a 700, a 600, and a 500 are operational. A 900 ultrashield system is expected 1q/2006. Solution state NMR systems operate with cryoprobes.